Haematology

Haematology

Coloured Atlas

Basophilic Stippling

Basophilic Stippling
Courtesy of Dr. A. McLeod

Basophilic stippling are inclusions of aggregated ribosomes. They are a non-specific finding that can indicate regenerative anemias, such as lead poisoning and thalassemia among others.

Anema – Microcytic

Iron Deficiency Anemia
Microcytosis and hypochromia of red blood cells. Note increased area of central pallor.

Anema - Microcytic

Megaloblastic No.1

Megaloblastic Anemia (Hypersegmented Neutrophils)
Megaloblastic anemia is often a result of Vitamin B-12 or folate deficiency, it is characterized by the presence of I, ovalocytes (oval-shaped RBCs) and II, hypersegmented neutrophils, on peripheral blood smear.

Megaloblastic No.1

Megaloblastic No. 2

Megaloblastic Anemia (Oval macrocytes)
Megaloblastic anemia is often a result of Vitamin B-12 or folate deficiency, it is characterized by the presence of I, ovalocytes (oval-shaped RBCs) and II, hypersegmented neutrophils, on peripheral blood smear.

Megaloblastic No. 2

Sickle Cell

Sickle Cell Anemia
Elongated, crescent-shaped and sickle RBCs. Note target cells (arrow) and Howell-Jolly body (both due to autosplenectomy secondary to repeated splenic infarcts). (Courtesy of Dr. M. Reis)

Sickle Cell

Microangiopathic Hemolytic

Microangiopathic Hemolytic Anemia
Fragmented RBCs (schistocytes). Note Helmet cell and triangle-shaped cell (arrows).

Microangiopathic Hemolytic

Hereditary Spherocytosis

Small, round, densely staining red blood cells with no central area of pallor.

Hereditary Spherocytosis

Autoimmune Hemolytic

Autoimmune Hemolytic Anemia
Agglutination of red blood cells (arrow).

Autoimmune Hemolytic

Plasma Cell Myeloma

Note Rouleaux

Plasma Cell Myeloma

Myelogenous Leukemia

Acute Myelogenous Leukemia. Note blast cell with Auer rod.

Myelogenous Leukemia

Myelofibrosis

Tear drop RBCs (poikilocytes) in the centre field. (Courtesy of Dr. D. Sutton)

Myelofibrosis

Multiple Myeloma

(Bone Marrow)
Plasma cells in marrow. Note Binucleate malignant plasma cell.

Multiple Myeloma

Lymphocytic Leukemia

Chronic Lymphocytic Leukemia. Increased number of small, well-differentiated lymphocytes. Note “smudge cells.”

Lymphocytic Leukemia