by Tim Milligan | Nov 11, 2015 | Hematologic Malignancies
(Lymph Node) Reed-Sternberg cell (arrow) is large and bilobed or binucleate. Prominent within the mirror-image nuclei are giant inclusion-like nucleoli (“owl’s eyes”).
by Tim Milligan | Nov 11, 2015 | Hematologic Malignancies
Chronic Myelogenous Leukemia Increased numbers of granulocytes and their precursors. Note most WBCs are band forms of segmented granulocytes.
by Tim Milligan | Nov 11, 2015 | Anema - Microcytic
Basophilic stippling are inclusions of aggregated ribosomes. They are a non-specific finding that can indicate regenerative anemias, such as lead poisoning and thalassemia among others.
by Tim Milligan | Nov 11, 2015 | Anemia-Macrocytic
Megaloblastic Anemia (Hypersegmented Neutrophils) Megaloblastic anemia is often a result of Vitamin B-12 or folate deficiency, it is characterized by the presence of I, ovalocytes (oval-shaped RBCs) and II, hypersegmented neutrophils, on peripheral blood...
by Tim Milligan | Nov 11, 2015 | Anemia-Macrocytic
Megaloblastic Anemia (Oval macrocytes) Megaloblastic anemia is often a result of Vitamin B-12 or folate deficiency, it is characterized by the presence of I, ovalocytes (oval-shaped RBCs) and II, hypersegmented neutrophils, on peripheral blood smear.
by Tim Milligan | Nov 11, 2015 | Anemia-Hemolytic
Sickle Cell Anemia Elongated, crescent-shaped and sickle RBCs. Note target cells (arrow) and Howell-Jolly body (both due to autosplenectomy secondary to repeated splenic infarcts). (Courtesy of Dr. M. Reis)
