Plasma Cell Myeloma
Note Rouleaux
Myelogenous Leukemia
Acute Myelogenous Leukemia. Note blast cell with Auer rod.
Myelofibrosis
Tear drop RBCs (poikilocytes) in the centre field. (Courtesy of Dr. D. Sutton)
Multiple Myeloma
(Bone Marrow)
Plasma cells in marrow. Note Binucleate malignant plasma cell.
Lymphocytic Leukemia
Chronic Lymphocytic Leukemia. Increased number of small, well-differentiated lymphocytes. Note “smudge cells.”
Lymphoblastic Leukemia
Acute Lymphoblastic Leukemia
Round or convoluted nuclei, absence of cytoplasmic granules, and high nuclear to cytoplasmic ratio. (Courtesy of Dr. D. Sutton).
Hodgkins Lymphoma
(Lymph Node)
Reed-Sternberg cell (arrow) is large and bilobed or binucleate. Prominent within the mirror-image nuclei are giant inclusion-like nucleoli (“owl’s eyes”).
Chronic Myelogenous Leukemia
Chronic Myelogenous Leukemia
Increased numbers of granulocytes and their precursors. Note most WBCs are band forms of segmented granulocytes.
Basophilic Stippling
Basophilic stippling are inclusions of aggregated ribosomes. They are a non-specific finding that can indicate regenerative anemias, such as lead poisoning and thalassemia among others.
Megaloblastic No.1
Megaloblastic Anemia (Hypersegmented Neutrophils)
Megaloblastic anemia is often a result of Vitamin B-12 or folate deficiency, it is characterized by the presence of I, ovalocytes (oval-shaped RBCs) and II, hypersegmented neutrophils, on peripheral blood smear.
